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In this paper, a sensor fault-tolerant control (FTC) scheme using robust model predictive control (MPC) and set theoretic fault detection and isolation (FDI) is proposed. The MPC controller is used to both robustly control the plant and actively guarantee fault isolation (FI). In this scheme, fault detection (FD) is passive by interval observers, while fault isolation (FI) is active by MPC. The advantage of the proposed approach consists in using MPC to actively decouple the effect of sensor faults on the outputs such that one output component only corresponds to one sensor fault in terms of FI, which can utilize the feature of sensor faults for FI. A numerical example is used to illustrate the effectiveness of the proposed scheme.Postprint (author’s final draft